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( Correspondence author marked with asterisk *)
( Bai lab members in bold, # equal contribution).
2021
Long non-coding RNA regulation of spermatogenesis and endosomal processes via the spectrin cytoskeleton in Drosophila
Bouska M*, Bai H*. 2021. G3: Genes, Genomes, Genetics. https://doi.org/10.1093/g3journal/jkab080
FOXO regulates neuromuscular junction homeostasis during Drosophila aging.
Birnbaum A*, Sodders M, Bouska M, Chang K, Kang P, McNeill E, Bai H*. 2021. Frontiers in Aging Neuroscience. doi.org/10.3389/fnagi.2020.567861.
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)
Klionsky DJ, ..., Bai H, et al. 2021. Autophagy.
2020
Peroxisome import stress impairs ribosome biogenesis and induces endoplasmic reticulum genes
Huang K#, Kim J#, Bai H*. 2020. bioRxiv. doi: https://doi.org/10.1101/2020.11.19.390609. (Preprint)
Liver hepatokines and peroxisomes as therapeutic targets for cardiovascular diseases
Huang K*, Bai H*. 2020. Future Cardiology.
Impaired peroxisomal import in Drosophila oenocytes causes cardiac dysfunction by inducing upd3 as a peroxikine.
Huang K, Miao T, Chang K, Kim J, Kang P, Jiang Q, Simmonds AJ, Di Cara F, and Bai H*. 2020. Nature Communications. doi:10.1038/s41467-020-16781-w
Long non-coding RNA regulation of spermatogenesis and endosomal processes via the spectrin cytoskeleton in Drosophila
Bouska M*, Bai H*. 2020. bioRxiv. doi.org/10.1101/2020.07.24.220640. (Preprint)
FOXO regulates neuromuscular junction homeostasis during Drosophila aging.
Birnbaum A*, Chang K, Bai H*. 2020. bioRxiv. doi.org/10.1101/2020.04.13.040121. (Preprint)
2019
TGFB-INHB/activin signaling regulates age-dependent autophagy and cardiac health through inhibition of MTORC2
Chang K#, Kang P#, Liu Y, Huang K, Miao T, Sagona AP, Nezis IP, Bodmer R, Ocorr K, Bai H*. 2019. Autophagy.
Physiological functions of a methuselah-like G protein coupled receptor in Lymantria dispar Linnaeus.
Cao C, Sun L, Du H, Moural T, Bai H, Liu P, Zhu F*. 2019. Pesticide Biochemistry and Physiology. https://doi.org/10.1016/j.pestbp.2019.07.002.
Impaired peroxisomal import in Drosophila hepatocyte-like cells induces cardiac dysfunction through the pro-inflammatory cytokine Upd3.
Huang K, Miao T, Chang K, Kang P, Jiang Q, Simmonds AJ, Di Cara F, and Bai H*. 2019. bioRxiv. 659128. https://doi.org/10.1101/659128. (Preprint)
Age-dependent changes in transcription factor FOXO targeting in female Drosophila.
Birnbaum A, Wu X, Tatar M, Liu N*, Bai H*. 2019. Frontiers in Genetics, Genetics of Aging. doi: 10.3389/fgene.2019.00312.
Organelle Aging: Lessons from Model Organisms.
Bouska M, Huang K, Kang P, Bai H*. 2019. Journal of Genetics and Genomics. https://doi.org/10.1016/j.jgg.2019.03.011.
A determining factor for insect feeding preference in the silkworm, Bombyx mori.
Zhang ZJ, Zhang SS, Niu BL, Ji DF, Liu XJ, Li MW, Bai H, Palli SR, Wang CZ, Tan AJ. 2019. PLoS Biology. 17(2):e3000162. doi: 10.1371.
RiboTag translatomic profiling of Drosophila oenocytes under aging and induced oxidative stress.
Huang K*, Chen W, Zhu F, Li P, Kapahi P, Bai H*. 2019. BMC Genomics. 20(1):50. doi: 10.1186/s12864-018-5404-4. PMID: 30651069.
2018
Age-dependent changes in transcription factor FOXO targeting in Drosophila melanogaster.
Birnbaum A, Wu X, Tatar M, Liu N*, Bai H*. 2018. bioRxiv. doi: https://doi.org/10.1101/456426. (Preprint)
2017
Activin Signaling Regulates Autophagy and Cardiac Aging through mTORC2.
Chang K, Kang P, Liu Y, Huang K, Miao T, Taylor E, Sagona AP, Nezis IP, Bodmer R, Ocorr K, Bai H*. 2017. biorxiv. (Preprint)
Drosophila Kruppel homolog 1 represses lipolysis through interaction with dFOXO.
Kang P, Chang K, Liu Y, Bouska M, Birnbaum A, Karashchuk G, Thakore R, Zheng W, Post S, Brent C, Li S, Tatar M*, Bai H*. 2017. Scientific Reports. PMID:29180716.
The FOXO transcription factor controls insect growth and development by regulating juvenile hormone degradation in the silkworm, Bombyx mori.
Zeng B, Huang Y, Xu J, Shiotsuki T, Bai H, Palli SR, Huang Y, Tan A*. 2017. Journal Biological Chemistry. PMID:28490635. PMCID:PMC5512063.
2016
Identification of G protein-coupled receptors required for vitellogenin uptake into the oocytes of the red flour beetle, Tribolium castaneum.
Bai H *, Palli SR*. 2016. Scientific Reports. 6:27648. doi: 10.1038/srep27648. PMCID: PMC489975.7.
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Klionsky DJ, ..., Bai H, et al. 2016. Autophagy.12(1):1-222. PMCID: PMC4835977.
2015
Drosophila longevity assurance conferred by reduced insulin receptor substrate chico requires 4E-BP.
Bai H, Post S, Kang P, Tatar M*. 2015. PLoS One. 10(8):e0134415. PMCID: PMC4529185.
Tequila regulates insulin-like signaling and extends life span in Drosophila melanogaster.
Huang CW, Wang HD, Bai H, Wu MS, Yen JH, Tatar M, Fu TF, Wang PY*. 2015. Journal of Gerontology: Biological Sciences. 70(12):1461-9. PMCID: PMC4675830.
2013
Activin signaling targeted by insulin/dFOXO regulates aging and muscle proteostasis in Drosophila.
Bai H, Kang P, Hernandez AM, Tatar M*. 2013. PLoS Genetics. 9(11): e1003941. PMCID: PMC3820802.
Juvenile hormone regulation of Drosophila aging.
Yamamoto R, Bai H, Dolezal AG, Amdam G, Tatar M*. 2013. BMC Biology. 11:85. PMCID: PMC3726347.
2012
Drosophila insulin-like peptide-6 (dilp6) expression from fat body extends lifespan and represses secretion of Drosophila insulin-like peptide-2 from the brain.
Bai H, Kang P, Tatar M*. 2012. Aging Cell. 11(6):978-85. PMCID: PMC3500397.
Minibrain/Dyrk1a regulates food intake through the Sir2-FOXO-sNPF/NPY pathway in Drosophila and mammals.
Hong S-H, Lee K-H, Kwak S-H, Kim A-K, Bai H, Jung M-S, Kwon O-Y, Song W-J, Tatar M, Yu K*. 2012. PLoS Genetics. 8(8): e1002857. PMCID: PMC3410862.
2011
Juvenile hormone regulates vitellogenin gene expression through insulin-like peptide signaling pathway in the red flour beetle, Tribolium castaneum.
Sheng Z, Xu J, Bai H, Zhu F, Palli SR*. 2011. Journal of Biological Chemistry. 286(49):41924-36. PMCID: PMC3234905.
Large-scale RNAi screen of G protein-coupled receptors involved in larval growth, molting and metamorphosis in the red flour beetle.
Bai H, Zhu F, Shah K, Palli SR*. 2011. BMC Genomics, 12(1):388. PMCID: PMC3163568.
2010
Mode of action of methoprene in affecting female reproduction in the African malaria mosquito, Anopheles gambiae.
Bai H, Gelman D. B, Palli SR*. 2010. Pest Management Science, 66(9):936-43. PMCID: PMC2928151.
Functional characterization of bursicon receptor and genome-wide analysis for identification of genes affected by bursicon receptor RNAi.
Bai H, Palli SR*. 2010. Developmental Biology, 344(1):248-58. PMCID: PMC2909337.
A brain-specific cytochrome P450 responsible for the majority of deltamethrin resistance in the QTC279 strain of Tribolium castaneum.
Zhu F, Parthasarathy R, Bai H, Woitheb K, Kaussmannb M, Nauenb R, Harrison DA, Palli SR*. 2010. The Proceedings of the National Academy of Sciences of the U.S.A., 107(19):8557-62. PMCID: PMC2889294.
Juvenile hormone regulation of vitellogenin synthesis in the red flour beetle, Tribolium castaneum.
Parthasarathy R, Sun Z, Bai H, Palli SR*. 2010. Insect Biochemistry and Molecular Biology, 40(5):405-14. PMCID: PMC2875371.
2009
The mandibular organ in crustacean and a radiochemical assay for methyl farnesoate.
Lu J, Chang G, Wu X, Bai H, Zhao W, Cheng Y*. 2009. Fisheries Science, 28(2):113-116.
2008
Transcription factor broad suppresses precocious development of adult structures during larval-pupal metamorphosis in the red flour beetle, Tribolium castaneum.
Parthasarathy R, Tan A, Bai H, Palli SR*. 2008. Mechanisms of Development, 125(3-4):299-313. PMCID: PMC3556786.
2007
Identification and characterization of juvenile hormone esterase gene from the yellow fever mosquito, Aedes aegypti.
Bai H, Parthasarathy R, Palli SR*. 2007. Insect Biochemistry and Molecular Biology, 37(8):829-37. PMCID: PMC2020842.
2006
Mechanisms of midgut remodeling: Juvenile hormone analog methoprene blocks midgut metamorphosis by modulating ecdysone action.
Wu Y, Parthasarathy R, Bai H, Palli SR*. 2006. Mechanisms of Development, 123(7):530-547. PMID: 16829058.
In vitro regulation of hormone biosynthesis of the mandibular organ in crayfish, Procambarus clarkia.
Lu J, Bai H, Cheng Y, Zhao W*. 2006. Journal of Fisheries of China. Vol.13, No.3, 471-474.
2002
The regulation of methyl farnesoate biosynthesis in Procambarus clarkii.
Zhao W*, Bai H, Lu J. 2002. Journal of Fisheries of China. Vol.26, Suppl. 1-6.
Effects of the Chinese herb, Radix polygoni multiflori on MPTP-induced mouse model of Parkinson’s disease.
Yuan C*, Bai H, Yang F. 2002. Journal of East China Normal University (Natural Science). No.3, 95-98.
2001
The biosynthesis of methyl farnesoate by the mandibular organ in crayfish, Procambarus clarkii.
Zhao W*, Bai H. 2001. Journal of Fisheries of China. Vol.25, No.3, 193-196.
1999
Changes in progesterone contents of the ovary and mandibular organ in crayfish during vitellogenesis.
Zhao W*, Bai H, Ma X. 1999. Journal of Shanghai Fisheries University. Vol.8, No.3, 232-236.
Book chapters
Bai H, 2012. Genome-Wide RNAi Screen for the Discovery of Gene Function, Novel Therapeutical Targets and Agricultural Applications. In: Functional genomics. Meroni G. and Petrera F. (ed). InTech. DOI: 10.5772/49945
Bai H, Palli SR. 2012. G protein-coupled receptors as target sites for insecticide discovery. In: Advanced Technologies for Controlling Insect Pests. Ishaaya I, Palli S.R, Horowitz A.R. (ed). Springer Science.
Palli SR, Bai H, Wigginton J. 2011. Insect genomics and beyond. In: Insect Biochemistry and Molecular Biology. Gilbert L. (ed). Springer Science.
Garry NH, Hill RJ, Dedos SG, Swevers L, Latrou K, Tan A, Parthasarathy R, Bai H, Zhang Z, Palli SR. 2009. Applications of RNA interference in ecdysone research. In: Ecdysone, structures and functions. G. Smaghhe (ed). Springer Science, 205-227.
( Bai lab members in bold, # equal contribution).
2021
Long non-coding RNA regulation of spermatogenesis and endosomal processes via the spectrin cytoskeleton in Drosophila
Bouska M*, Bai H*. 2021. G3: Genes, Genomes, Genetics. https://doi.org/10.1093/g3journal/jkab080
FOXO regulates neuromuscular junction homeostasis during Drosophila aging.
Birnbaum A*, Sodders M, Bouska M, Chang K, Kang P, McNeill E, Bai H*. 2021. Frontiers in Aging Neuroscience. doi.org/10.3389/fnagi.2020.567861.
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)
Klionsky DJ, ..., Bai H, et al. 2021. Autophagy.
2020
Peroxisome import stress impairs ribosome biogenesis and induces endoplasmic reticulum genes
Huang K#, Kim J#, Bai H*. 2020. bioRxiv. doi: https://doi.org/10.1101/2020.11.19.390609. (Preprint)
Liver hepatokines and peroxisomes as therapeutic targets for cardiovascular diseases
Huang K*, Bai H*. 2020. Future Cardiology.
Impaired peroxisomal import in Drosophila oenocytes causes cardiac dysfunction by inducing upd3 as a peroxikine.
Huang K, Miao T, Chang K, Kim J, Kang P, Jiang Q, Simmonds AJ, Di Cara F, and Bai H*. 2020. Nature Communications. doi:10.1038/s41467-020-16781-w
Long non-coding RNA regulation of spermatogenesis and endosomal processes via the spectrin cytoskeleton in Drosophila
Bouska M*, Bai H*. 2020. bioRxiv. doi.org/10.1101/2020.07.24.220640. (Preprint)
FOXO regulates neuromuscular junction homeostasis during Drosophila aging.
Birnbaum A*, Chang K, Bai H*. 2020. bioRxiv. doi.org/10.1101/2020.04.13.040121. (Preprint)
2019
TGFB-INHB/activin signaling regulates age-dependent autophagy and cardiac health through inhibition of MTORC2
Chang K#, Kang P#, Liu Y, Huang K, Miao T, Sagona AP, Nezis IP, Bodmer R, Ocorr K, Bai H*. 2019. Autophagy.
Physiological functions of a methuselah-like G protein coupled receptor in Lymantria dispar Linnaeus.
Cao C, Sun L, Du H, Moural T, Bai H, Liu P, Zhu F*. 2019. Pesticide Biochemistry and Physiology. https://doi.org/10.1016/j.pestbp.2019.07.002.
Impaired peroxisomal import in Drosophila hepatocyte-like cells induces cardiac dysfunction through the pro-inflammatory cytokine Upd3.
Huang K, Miao T, Chang K, Kang P, Jiang Q, Simmonds AJ, Di Cara F, and Bai H*. 2019. bioRxiv. 659128. https://doi.org/10.1101/659128. (Preprint)
Age-dependent changes in transcription factor FOXO targeting in female Drosophila.
Birnbaum A, Wu X, Tatar M, Liu N*, Bai H*. 2019. Frontiers in Genetics, Genetics of Aging. doi: 10.3389/fgene.2019.00312.
Organelle Aging: Lessons from Model Organisms.
Bouska M, Huang K, Kang P, Bai H*. 2019. Journal of Genetics and Genomics. https://doi.org/10.1016/j.jgg.2019.03.011.
A determining factor for insect feeding preference in the silkworm, Bombyx mori.
Zhang ZJ, Zhang SS, Niu BL, Ji DF, Liu XJ, Li MW, Bai H, Palli SR, Wang CZ, Tan AJ. 2019. PLoS Biology. 17(2):e3000162. doi: 10.1371.
RiboTag translatomic profiling of Drosophila oenocytes under aging and induced oxidative stress.
Huang K*, Chen W, Zhu F, Li P, Kapahi P, Bai H*. 2019. BMC Genomics. 20(1):50. doi: 10.1186/s12864-018-5404-4. PMID: 30651069.
2018
Age-dependent changes in transcription factor FOXO targeting in Drosophila melanogaster.
Birnbaum A, Wu X, Tatar M, Liu N*, Bai H*. 2018. bioRxiv. doi: https://doi.org/10.1101/456426. (Preprint)
2017
Activin Signaling Regulates Autophagy and Cardiac Aging through mTORC2.
Chang K, Kang P, Liu Y, Huang K, Miao T, Taylor E, Sagona AP, Nezis IP, Bodmer R, Ocorr K, Bai H*. 2017. biorxiv. (Preprint)
Drosophila Kruppel homolog 1 represses lipolysis through interaction with dFOXO.
Kang P, Chang K, Liu Y, Bouska M, Birnbaum A, Karashchuk G, Thakore R, Zheng W, Post S, Brent C, Li S, Tatar M*, Bai H*. 2017. Scientific Reports. PMID:29180716.
The FOXO transcription factor controls insect growth and development by regulating juvenile hormone degradation in the silkworm, Bombyx mori.
Zeng B, Huang Y, Xu J, Shiotsuki T, Bai H, Palli SR, Huang Y, Tan A*. 2017. Journal Biological Chemistry. PMID:28490635. PMCID:PMC5512063.
2016
Identification of G protein-coupled receptors required for vitellogenin uptake into the oocytes of the red flour beetle, Tribolium castaneum.
Bai H *, Palli SR*. 2016. Scientific Reports. 6:27648. doi: 10.1038/srep27648. PMCID: PMC489975.7.
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Klionsky DJ, ..., Bai H, et al. 2016. Autophagy.12(1):1-222. PMCID: PMC4835977.
2015
Drosophila longevity assurance conferred by reduced insulin receptor substrate chico requires 4E-BP.
Bai H, Post S, Kang P, Tatar M*. 2015. PLoS One. 10(8):e0134415. PMCID: PMC4529185.
Tequila regulates insulin-like signaling and extends life span in Drosophila melanogaster.
Huang CW, Wang HD, Bai H, Wu MS, Yen JH, Tatar M, Fu TF, Wang PY*. 2015. Journal of Gerontology: Biological Sciences. 70(12):1461-9. PMCID: PMC4675830.
2013
Activin signaling targeted by insulin/dFOXO regulates aging and muscle proteostasis in Drosophila.
Bai H, Kang P, Hernandez AM, Tatar M*. 2013. PLoS Genetics. 9(11): e1003941. PMCID: PMC3820802.
Juvenile hormone regulation of Drosophila aging.
Yamamoto R, Bai H, Dolezal AG, Amdam G, Tatar M*. 2013. BMC Biology. 11:85. PMCID: PMC3726347.
2012
Drosophila insulin-like peptide-6 (dilp6) expression from fat body extends lifespan and represses secretion of Drosophila insulin-like peptide-2 from the brain.
Bai H, Kang P, Tatar M*. 2012. Aging Cell. 11(6):978-85. PMCID: PMC3500397.
Minibrain/Dyrk1a regulates food intake through the Sir2-FOXO-sNPF/NPY pathway in Drosophila and mammals.
Hong S-H, Lee K-H, Kwak S-H, Kim A-K, Bai H, Jung M-S, Kwon O-Y, Song W-J, Tatar M, Yu K*. 2012. PLoS Genetics. 8(8): e1002857. PMCID: PMC3410862.
2011
Juvenile hormone regulates vitellogenin gene expression through insulin-like peptide signaling pathway in the red flour beetle, Tribolium castaneum.
Sheng Z, Xu J, Bai H, Zhu F, Palli SR*. 2011. Journal of Biological Chemistry. 286(49):41924-36. PMCID: PMC3234905.
Large-scale RNAi screen of G protein-coupled receptors involved in larval growth, molting and metamorphosis in the red flour beetle.
Bai H, Zhu F, Shah K, Palli SR*. 2011. BMC Genomics, 12(1):388. PMCID: PMC3163568.
2010
Mode of action of methoprene in affecting female reproduction in the African malaria mosquito, Anopheles gambiae.
Bai H, Gelman D. B, Palli SR*. 2010. Pest Management Science, 66(9):936-43. PMCID: PMC2928151.
Functional characterization of bursicon receptor and genome-wide analysis for identification of genes affected by bursicon receptor RNAi.
Bai H, Palli SR*. 2010. Developmental Biology, 344(1):248-58. PMCID: PMC2909337.
A brain-specific cytochrome P450 responsible for the majority of deltamethrin resistance in the QTC279 strain of Tribolium castaneum.
Zhu F, Parthasarathy R, Bai H, Woitheb K, Kaussmannb M, Nauenb R, Harrison DA, Palli SR*. 2010. The Proceedings of the National Academy of Sciences of the U.S.A., 107(19):8557-62. PMCID: PMC2889294.
Juvenile hormone regulation of vitellogenin synthesis in the red flour beetle, Tribolium castaneum.
Parthasarathy R, Sun Z, Bai H, Palli SR*. 2010. Insect Biochemistry and Molecular Biology, 40(5):405-14. PMCID: PMC2875371.
2009
The mandibular organ in crustacean and a radiochemical assay for methyl farnesoate.
Lu J, Chang G, Wu X, Bai H, Zhao W, Cheng Y*. 2009. Fisheries Science, 28(2):113-116.
2008
Transcription factor broad suppresses precocious development of adult structures during larval-pupal metamorphosis in the red flour beetle, Tribolium castaneum.
Parthasarathy R, Tan A, Bai H, Palli SR*. 2008. Mechanisms of Development, 125(3-4):299-313. PMCID: PMC3556786.
2007
Identification and characterization of juvenile hormone esterase gene from the yellow fever mosquito, Aedes aegypti.
Bai H, Parthasarathy R, Palli SR*. 2007. Insect Biochemistry and Molecular Biology, 37(8):829-37. PMCID: PMC2020842.
2006
Mechanisms of midgut remodeling: Juvenile hormone analog methoprene blocks midgut metamorphosis by modulating ecdysone action.
Wu Y, Parthasarathy R, Bai H, Palli SR*. 2006. Mechanisms of Development, 123(7):530-547. PMID: 16829058.
In vitro regulation of hormone biosynthesis of the mandibular organ in crayfish, Procambarus clarkia.
Lu J, Bai H, Cheng Y, Zhao W*. 2006. Journal of Fisheries of China. Vol.13, No.3, 471-474.
2002
The regulation of methyl farnesoate biosynthesis in Procambarus clarkii.
Zhao W*, Bai H, Lu J. 2002. Journal of Fisheries of China. Vol.26, Suppl. 1-6.
Effects of the Chinese herb, Radix polygoni multiflori on MPTP-induced mouse model of Parkinson’s disease.
Yuan C*, Bai H, Yang F. 2002. Journal of East China Normal University (Natural Science). No.3, 95-98.
2001
The biosynthesis of methyl farnesoate by the mandibular organ in crayfish, Procambarus clarkii.
Zhao W*, Bai H. 2001. Journal of Fisheries of China. Vol.25, No.3, 193-196.
1999
Changes in progesterone contents of the ovary and mandibular organ in crayfish during vitellogenesis.
Zhao W*, Bai H, Ma X. 1999. Journal of Shanghai Fisheries University. Vol.8, No.3, 232-236.
Book chapters
Bai H, 2012. Genome-Wide RNAi Screen for the Discovery of Gene Function, Novel Therapeutical Targets and Agricultural Applications. In: Functional genomics. Meroni G. and Petrera F. (ed). InTech. DOI: 10.5772/49945
Bai H, Palli SR. 2012. G protein-coupled receptors as target sites for insecticide discovery. In: Advanced Technologies for Controlling Insect Pests. Ishaaya I, Palli S.R, Horowitz A.R. (ed). Springer Science.
Palli SR, Bai H, Wigginton J. 2011. Insect genomics and beyond. In: Insect Biochemistry and Molecular Biology. Gilbert L. (ed). Springer Science.
Garry NH, Hill RJ, Dedos SG, Swevers L, Latrou K, Tan A, Parthasarathy R, Bai H, Zhang Z, Palli SR. 2009. Applications of RNA interference in ecdysone research. In: Ecdysone, structures and functions. G. Smaghhe (ed). Springer Science, 205-227.